Consideraçöes a respeito da cistite eosinofílica / Eosinophilic cystitis

Eosinophilic cystitis is a rare bladder disorder that was first reported in 1960 and can be diagnosed in children or adults. Its cause is unknown and usually presents with hematuria, supra pubic pain, sysuria and frequency. We have made an extensive literature review and we reported on 2 illustrative cases. The first case was a man presented with hematuria; a computed tomography, shown expansive process with a mass suggesting infiltration of the perivesical tissues. A biopsy was done and the pathological diagnosis was eosinophilic cystitis. The patient was treated with steroids. Later on, he had an episode of hematuria on the left ureteral orifice and a nephrouretectomy showed grade 2 urothelial carcinoma of the ureter. The second case is a child with neurogenic bladder due to myelomeningocele who had a cystostomy since the age of 5 months. Surgery was performed, including partial cystectomy with an ileal neobladder. The anatomopathological diagnosis was eosinophilic cystitis. The different classifications of eosinophilic cystitis were presented and discussed. The diagnosis of this entity can only be made by microscopic examination which shows mucosal edema or fibrosis, a polymorphous infiltrate rich in eosinophils and sometimes replacement of the bladder muscle by fibrotic tissue

Avaliaçäo da metodologia diagnóstica de ovulaçäo / Evaluation of the methods for the diagnosis of ovulation

Neste trabalho analisamos os diferentes métodos utilizados na prática clínica diária para o diagnóstico da ovulaçao, em dois ciclos consecutivos, e observamos que a monitorizaçao do ciclo através da avaliaçao do muco cervical e ultra-sonografia pélvica apresentou os melhores resultados, que foram coincidentes entre si.

Comparaçäo entre os diversos métodos utilizados na prática clínica para avaliaçäo da fase lútea / Comparison of different methods used in clinical practice for luteal phase evaluation

Neste trabalho, avaliamos a metodologia empregada para o diagnóstico dos defeitos da fase lútea em dois ciclos consecutivos; e pelos achados concluímos que a biópsia de endométrio é o melhor método de que dispomos na prática clínica. A dosagem da progesterona plasmática deve ser utilizada como um método complementar no seu diagnóstico.

Monitorizaçäo do transplante renal: revisäo dos métodos de investigaçäo da disfunçäo do enxerto / Monitoring of renal transplant: review of methods used to investigate graft dysfunction

Os autores revisam o tema Monitorizaçao do Transplante Renal através de uma análise crítica de vários métodos laboratoriais de investigaçao da disfunçao do enxerto renal. Sao analisadas as vantagens e desvantagens, as indicaçoes e as limitaçoes do exame do sedimento urinário, o significado da eosinofilia, as dosagens plasmáticas e urinária da neopterina e da beta-2-microglobulina, o valor da pressao intra-renal, os métodos de diagnóstico por imagem, a biópsia renal convensional, a "minicore biopsy" e a punçao aspirativa por agulha fina.